Statistical Analysis of Cost-Effective - Hardcover

by Andrew R. Willan (Author), Andrew H. Briggs (Author)

The statistical analysis of cost-effectiveness data is becoming increasingly important within health and medical research. Statistical Analysis of Cost-Effectiveness Data provides a practical book that synthesises the huge amount of research that has taken place in the area over the last two decades.

Comprising an up-to-date overview of the statistical analysis of cost-effectiveness data, the book is supported by numerous worked examples from the author's own experience. It has been written in a style suitable for medical statisticians and health care professionals alike. Key features include:

• an overview of statistical methods used in the analysis of cost-effectiveness data.
• coverage of Bayesian methodology.
• illustrated throughout by worked examples using real data.
• suitability for health care professionals with limited statistical knowledge.
• discussion of software used for data analysis.

An essential reference for biostatisticians and health economists engaged in cost-effectiveness analysis of health-care interventions, both in academia and industry. Also of interest to graduate students of biostatistics, public health and economics.

Back Jacket

Statistical Analysis of Cost-effectiveness Data

Cost-effectiveness analysis is the simultaneous Statistical comparison of two or more groups with respect to costs and effectiveness. A prime example of this is the comparison of health-care interventions, where there is a growing expectation from policymakers that evidence supporting the cost-effectiveness of new interventions be provided along with customary data on efficacy and safety. Statistical Analysis of Cost-effectiveness Data provides an overview of the statistical methods used in such analysis and gives an illustrated summary of the key developments in statistical issues related to cost-effectiveness comparisons, over the last decade.

• Provides an up-to-date overview of statistical methods used in the analysis of cost-effectiveness data.
• Discusses all the major issues in the field, including:
• Parameter estimation for both censored and uncensored data;
• Making inference using cost-effectiveness ratios;
• Incremental net benefit plots and cost-effectiveness ratios;
• Incremental net benefit plots and cost-effectiveness acceptability curves;
• Covariate adjustment and sub-group analyses;
• Multinational trials;
• Sample size determinations using both classical and Bayesian approaches.
• Illustrated throughout by worked examples from the authors' own experiences.

Statistical Analysis of Cost-effectiveness Data is ideal for biostatisticians and health economists both in academia and industry. There is also much of use for graduate students of biostatistics, public health and economics, as well as individuals working in government regulator agencies.

STATISTICS IN PRACTICE

A series of practical books outlining the use of statistical techniques in a wide range of applications areas:

• HUMAN AND BIOLOGICAL SCIENCES
• EARTH AND ENVIRONMENTAL SCIENCES
• INDUSTRY, COMMERCE AND FINANCE

Author Biography

Dr.Andrew R. Willan is an academic biostatistician and clinical trial methodologist, and currently holds the positions of Senior Scientist Emeritus at SickKids Research Institute, Professor of Biostatistics in the Dalla Lana School of Public Health at the University of Toronto, and Professor Emeritus in the Department of Clinical Epidemiology and Biostatistics at McMaster University. His contributions to statistical methodology include publications in the areas of cost-effectiveness analysis, value of information methods, management trials, crossover trials, non-nested regression analysis and bivariate response models. Dr. Willan has been particularly instrumental in developing the field of statistical analysis of cost-effectiveness data with twenty peer-review articles and a book, co-authored with Professor Andy Briggs, in the Wiley Statistics in Practice series, entitled Statistical Analysis of Cost-effectiveness Data.